The Gut-Skin Axis: A Functional Medicine Perspective

The gut microbiome, which is the collection of trillions of bacteria that populate the human digestive tract, is the main hub of communication with the rest of the body, including the skin. Therefore, skin conditions often have an underlying cause rooted in the gut. In functional medicine, where we frequently observe concurrent gut and skin imbalances, we refer to this relationship as the gut-skin axis. Or, as the saying (maybe just my saying?) goes, if the gut ain’t happy, ain’t nobody happy. Additionally, the skin itself (and other organs/body systems) has its own microbiome that protects us externally from pathogenic organisms. So, skin issues can result from gut microbiome imbalances (and a congested digestive system) and/or a disruption to the skin microbiome. Chronic skin conditions such as psoriasis, acne, and eczema are often a combination of both.

External & Internal Factors in Chronic Skin Conditions

Externally, studies have shown that Staphylococcus aureus bacteria are a common contributor to atopic dermatitis, a form of eczema. Streptococcus is a common trigger for psoriasis, an autoimmune skin condition, while Candida can be present with either condition. Most cases also have a genetic component, making some people more susceptible to a less efficient skin barrier, making them more susceptible to overgrowth of these organisms.

Internally, a host of bacteria, yeast, and parasites can impact skin health when they reproduce beyond what our beneficial gut bacterial strains can control. This happens most commonly 3–18 months after taking a prescription antibiotic, but can also be influenced by diet, stress, environment, and other medications like acid blockers and oral contraceptives. Candida and H. pylori are common culprits in cases of acne. When these organisms multiply beyond what the gut’s beneficial bacteria and immune system can contain, the intestinal lining becomes inflamed and eventually “leaky,” allowing allergens, undigested food, and pathogenic organisms to enter the bloodstream. This can cause systemic inflammation, contributing to skin imbalances.

Your skin is a reflection of your inner health. Explore the powerful connection between gut health and skin conditions like psoriasis, eczema, and acne, and how functional nutrition can address these concerns at their root.

The skin is the body’s largest organ, so it makes sense that when something is out of balance internally, the skin will eventually show it. Dehydration, nutrient deficiencies, food sensitivities, immune reactions to environmental allergens or toxins, and hormonal imbalances — we can see a reflection of these internal conditions in the skin.

Testing for Gut Imbalances & Skin Conditions

Addressing skin conditions like psoriasis, eczema, and acne requires proper testing and a multi-faceted functional approach. First, stool, breath, and/or Organic Acid (urine) tests can help identify gut dysbiosis and specific contributing organisms. The Organic Acid test measures metabolites in urine that provide insights into bacterial, fungal, and yeast overgrowth in the gut. Additional factors such as sluggish digestion, poor bile output from the liver, low beneficial gut bacteria, impaired cellular detoxification pathways, and poor nutritional status perpetuate the inflammation and irritation associated with skin imbalances. Micronutrient and food allergy/sensitivity testing can also be helpful in approaching skin conditions from all angles.

Once the root cause(s) are identified, herbal antifungals and antimicrobials, along with skin-supportive nutrients and digestive support, can help eradicate pathogenic organisms and rebalance gut bacteria. Supporting detoxification and digestion allows the body to heal more effectively. After 2–3 months in this phase, it is crucial to continue focusing on reducing inflammation further and restoring full balance to the gut and skin microbiomes. This can be achieved with additional nutrients like zinc, vitamins A and D, and key probiotic strains based on personalized stool test results. Lifestyle factors, including sleep, stress management, and diet, are also important to prevent recurrence or relapse of symptoms.

Conclusion: The Path to Clearer Skin Begins in the Gut

Addressing skin conditions from a functional nutrition perspective means recognizing the critical link between gut health and skin health through the gut-skin axis. By identifying and treating underlying imbalances in the gut microbiome, as well as supporting the skin microbiome, long-lasting improvements in chronic skin conditions can be achieved. If you are struggling with psoriasis, eczema, acne, or other skin concerns, consider working with a functional nutritionist to explore comprehensive testing and personalized treatment plans. Prioritizing gut health could be the key to healthier skin.

A Jumpstart Call is the perfect way to kick off your personalized journey toward optimal gut and skin health. During this 1-on-1 consultation, we’ll discuss your health history, pinpoint potential root causes, and outline the best next steps to help you feel and look your best.

Don’t wait—take the first step toward glowing skin today!